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Table 2 Ten most frequently listed roadblocks for implementation and development of alternatives

From: Policy driven changes in animal research practices: mapping researchers’ attitudes towards animal-free innovations using the Netherlands as an example

I Alternatives are not animal-free VI Pressure to conform
II Awareness is lacking VII Publishing in high-impact journals
III Costs of implementation VIII Reliability
IV Differences in regulation IX Research funding
V Ethical issues X Time/effort to develop alternatives