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Table 1 Overview of included studies

From: Professional medical writing support and the quality, ethics and timeliness of clinical trial reporting: a systematic review

First author, year Number of included studies Publication type Description of analysed articles
With PMWS Without PMWS
Gattrell, 2016 [15] 110 123 Peer-reviewed publication • Articles reporting RCT results published in BioMed Central journals
• Biomed Central journals have been used in previous studies of adherence to CONSORT guidelines [22]
Gattrell, 2016 [18] 110 123 Poster presentation • Articles reporting RCT results published in BioMed Central journals (same cohort of articles analysed in Gattrell et al. [15])
Gattrell, 2017 [17] 17 49 Poster presentation • Sub-analysis of outcomes reported in the top five medical journals comparing each article with its corresponding study protocol or clinical trial registry entry using publicly available COMPare data
• The COMPare project is evaluating outcome reporting in clinical trials by comparing publications with the respective registry entries [23]
Jacobs, 2010 [16] 152 69 Non-peer-reviewed publication • RCTs published between October 2004 and August 2009 in the journal Current Medical Research and Opinion
Current Medical Research and Opinion almost exclusively publishes industry-funded studies
Mills, 2017 [14] 66 397 Peer-reviewed publication • RCTs published between 2011 and 2014 in five high-impact medical journals: The New England Journal of Medicine, Annals of Internal Medicine, The Lancet, The BMJ and JAMA
• All included articles had been analysed in a cross-sectional study examining reporting quality of RCTs [24]
Shah, 2015 [20] 40 103 Poster presentation • Neuroscience and cardiology RCTs published between 2009 and 2014 in different journals from the Asia-Pacific region
Shah, 2016 [19] 404 392 Poster presentation • RCTs conducted to gain US FDA approval in 2014
• Innovative and novel drugs and new molecules approved by the FDA in 2014, identified in FDA reports
Woolley, 2006 [8] 60 940 Congress abstract • Original research articles published up to January 2005 from each of 10 high-impact factor, international, peer-reviewed medical journals from a range of therapeutic areas
  1. COMPare Centre for Evidence-Based Medicine Outcome Monitoring Project, CONSORT Consolidated Standards of Reporting Trials, FDA Food and Drug Administration, PMWS professional medical writing support, RCT randomized controlled trial