From: Publication and non-publication of clinical trials in PTSD: an overview
Variable | Median survival time (95% CI) | Chi-square | p value |
---|---|---|---|
Overall | 27 (24; 30) | Â | Â |
Randomised |  | χ2(1) = 6.15 | 0.013* |
 Yes | 26 (23; 29) |  |  |
 No | 39 (32; 46) |  |  |
Blinding |  | χ2(2) = 2.54 | 0.281 |
 Double blind | 30 (24; 36) |  |  |
 Single blind | 24 (21; 27) |  |  |
 Open label | 23 (26; 40) |  |  |
Intervention type |  | χ2(3) = 13.33 | 0.004* |
 Drug | 39 (28; 50) |  |  |
 Behavioural | 26 (23; 29) |  |  |
 Procedure/device(e.g. TMS) | 27 (24; 31) |  |  |
 Drug and behavioural | 20 (20; 34) |  |  |
Any control condition used (e.g. waitlist, TAU) |  | χ2(1) = 5.35 | 0.021* |
 Yes | 26 (23; 29) |  |  |
 No | 39 (33; 45) |  |  |
Placebo used |  | χ2(1) = 0.65 | 0.422 |
 Yes | 30 (24; 37) |  |  |
 No | 27 (24; 30) |  |  |
Comparator used |  | χ2(1) = 0.97 | 0.324 |
 Yes | 27 (23; 31) |  |  |
 No | 29 (24; 34) |  |  |
Number of study arms |  | χ2(2) = 6.75 | 0.034* |
 One | 44 (37; 52) |  |  |
 Two | 25 (22; 28) |  |  |
 Three to six | 30 (20; 40) |  |  |
Any sponsor university |  | χ2(1) = 4.99 | 0.026* |
 Yes | 24 (20; 28) |  |  |
 No | 32 (26; 38) |  |  |
Any sponsor hospital |  | χ2(1) = 0.08 | 0.776 |
 Yes | 29 (21; 37) |  |  |
 No | 27 (24; 30) |  |  |
Any sponsor governmental organisation |  | χ2(1) = 0.450 | 0.502 |
 Yes | 28 (24; 32) |  |  |
 No | 26 (22; 30) |  |  |
Any sponsor pharmaceutical/industry |  | χ2(1) = 2.896 | 0.086 |
 Yes | 40 (0; 83) |  |  |
 No | 27 (24; 31) |  |  |
Any sponsor non-commercial |  | χ2(1) = 0.90 | 0.344 |
 Yes | 34 (23; 45) |  |  |
 No | 27 (24; 30) |  |  |
Contact email provided |  | χ2(1) = 0.87 | 0.352 |
 Yes | 26 (23; 29) |  |  |
 No | 29 (24; 34) |  |  |
Are the results related to PTSD |  | χ2(1) = 0.26 | 0.613 |
 Yes | 27 (23; 31) |  |  |
 No | 39 (1; 77) |  |  |
PTSD-related outcome |  | χ2(3) = 1.80 | 0.615 |
 Primary | 31 (22; 40) |  |  |
 Secondary | 26 (23; 29) |  |  |
 Both primary and secondary | 25 (19; 31) |  |  |
Other (e.g. covariate, condition studied) | 30 (22; 38) | Â | Â |
Primary outcome measure/s |  | χ2(2) = 2.32 | 0.115 |
Positive | 26 (23; 29) | Â | Â |
 Null | 31 (25; 37) |  |  |
 Mixed | 23 (14; 32) |  |  |
Secondary outcome measure/s |  | χ2(2) = 1.50 | 0.473 |
Positive | 25 (21; 29) | Â | Â |
 Null | 29 (22; 36) |  |  |
 Mixed | 24 (20; 28) |  |  |
Registered before 2006 |  | χ2(1) = 0.32 | 0.573 |
 Yes | 31 (24; 39) |  |  |
 No | 27 (24; 30) |  |  |
Study registered before started |  | χ2(1) = 1.07 | 0.302 |
 Yes | 27 (23; 31) |  |  |
 No | 28 (24; 32) |  |  |
Study registered before completed |  | χ2(1) = 4.22 | 0.040* |
 Yes | 28 (24; 32) |  |  |
 No | 35 (26; 44) |  |  |